2cya

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{{Seed}}
 
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[[Image:2cya.png|left|200px]]
 
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==Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix==
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The line below this paragraph, containing "STRUCTURE_2cya", creates the "Structure Box" on the page.
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<StructureSection load='2cya' size='340' side='right'caption='[[2cya]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2cya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2cya| PDB=2cya | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cya OCA], [https://pdbe.org/2cya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cya RCSB], [https://www.ebi.ac.uk/pdbsum/2cya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cya ProSAT], [https://www.topsan.org/Proteins/RSGI/2cya TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYY_AERPE SYY_AERPE] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02009]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cya_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cya ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix===
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_16325203}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16325203 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16325203}}
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==About this Structure==
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2CYA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYA OCA].
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==Reference==
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Crystal structures of tyrosyl-tRNA synthetases from Archaea., Kuratani M, Sakai H, Takahashi M, Yanagisawa T, Kobayashi T, Murayama K, Chen L, Liu ZJ, Wang BC, Kuroishi C, Kuramitsu S, Terada T, Bessho Y, Shirouzu M, Sekine S, Yokoyama S, J Mol Biol. 2006 Jan 20;355(3):395-408. Epub 2005 Nov 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16325203 16325203]
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[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
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[[Category: Tyrosine--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Bessho, Y.]]
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[[Category: Bessho Y]]
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[[Category: Chen, L.]]
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[[Category: Chen L]]
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[[Category: Kobayashi, T.]]
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[[Category: Kobayashi T]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu S]]
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[[Category: Kuratani, M.]]
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[[Category: Kuratani M]]
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[[Category: Kuroishi, C.]]
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[[Category: Kuroishi C]]
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[[Category: Liu, Z J.]]
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[[Category: Liu ZJ]]
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[[Category: Murayama, K.]]
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[[Category: Murayama K]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Sakai H]]
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[[Category: Sakai, H.]]
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[[Category: Sekine SI]]
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[[Category: Sekine, S I.]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M.]]
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[[Category: Takahashi M]]
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[[Category: Takahashi, M.]]
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[[Category: Terada T]]
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[[Category: Terada, T.]]
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[[Category: Wang BC]]
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[[Category: Wang, B C.]]
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[[Category: Yanagisawa T]]
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[[Category: Yanagisawa, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Aminoacylation]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Tyrr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 16:53:09 2008''
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Current revision

Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix

PDB ID 2cya

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