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2ax3

From Proteopedia

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{{Seed}}
 
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[[Image:2ax3.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF A PUTATIVE CARBOHYDRATE KINASE (TM0922) FROM THERMOTOGA MARITIMA MSB8 AT 2.25 A RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_2ax3", creates the "Structure Box" on the page.
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<StructureSection load='2ax3' size='340' side='right'caption='[[2ax3]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ax3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AX3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ax3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ax3 OCA], [https://pdbe.org/2ax3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ax3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ax3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ax3 ProSAT], [https://www.topsan.org/Proteins/JCSG/2ax3 TOPSAN]</span></td></tr>
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{{STRUCTURE_2ax3| PDB=2ax3 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of a putative carbohydrate kinase (tm0922) from Thermotoga maritima at 2.25 A resolution===
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[https://www.uniprot.org/uniprot/NNR_THEMA NNR_THEMA] Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2AX3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AX3 OCA].
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<jmolCheckbox>
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[[Category: Thermotoga maritima msb8]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ax/2ax3_consurf.spt"</scriptWhenChecked>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Hypothetical protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Jcsg]]
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</jmolCheckbox>
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[[Category: Joint center for structural genomic]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ax3 ConSurf].
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[[Category: Protein structure initiative]]
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<div style="clear:both"></div>
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[[Category: Psi]]
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__TOC__
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[[Category: Structural genomic]]
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</StructureSection>
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[[Category: Tm0922]]
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[[Category: Large Structures]]
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[[Category: Thermotoga maritima MSB8]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 16:59:53 2008''
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Current revision

CRYSTAL STRUCTURE OF A PUTATIVE CARBOHYDRATE KINASE (TM0922) FROM THERMOTOGA MARITIMA MSB8 AT 2.25 A RESOLUTION

PDB ID 2ax3

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