2ysg

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{{Seed}}
 
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[[Image:2ysg.png|left|200px]]
 
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==Solution structure of the WW domain from the human syntaxin-binding protein 4==
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The line below this paragraph, containing "STRUCTURE_2ysg", creates the "Structure Box" on the page.
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<StructureSection load='2ysg' size='340' side='right'caption='[[2ysg]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ysg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YSG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ysg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ysg OCA], [https://pdbe.org/2ysg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ysg RCSB], [https://www.ebi.ac.uk/pdbsum/2ysg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ysg ProSAT], [https://www.topsan.org/Proteins/RSGI/2ysg TOPSAN]</span></td></tr>
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{{STRUCTURE_2ysg| PDB=2ysg | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/STXB4_HUMAN STXB4_HUMAN] Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/2ysg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ysg ConSurf].
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<div style="clear:both"></div>
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===Solution structure of the WW domain from the human syntaxin-binding protein 4===
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==See Also==
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*[[Syntaxin-binding protein|Syntaxin-binding protein]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2YSG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YSG OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Harada, T.]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T.]]
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[[Category: Harada T]]
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[[Category: Koshiba, S.]]
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[[Category: Kigawa T]]
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[[Category: Ohnishi, S.]]
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[[Category: Koshiba S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Ohnishi S]]
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[[Category: Sato, M.]]
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[[Category: Sato M]]
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[[Category: Tochio, N.]]
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[[Category: Tochio N]]
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[[Category: Watanabe, S.]]
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[[Category: Watanabe S]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nmr]]
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[[Category: Nppsfa]]
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[[Category: Protein binding]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Stxbp4]]
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[[Category: Synip]]
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[[Category: Ww domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 17:50:08 2008''
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Current revision

Solution structure of the WW domain from the human syntaxin-binding protein 4

PDB ID 2ysg

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Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ysg"
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