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3ckn

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{{Seed}}
 
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[[Image:3ckn.png|left|200px]]
 
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<!--
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==Crystal Structure of a Mycobacterial Protein==
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The line below this paragraph, containing "STRUCTURE_3ckn", creates the "Structure Box" on the page.
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<StructureSection load='3ckn' size='340' side='right'caption='[[3ckn]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ckn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_avium_subsp._paratuberculosis_K-10 Mycobacterium avium subsp. paratuberculosis K-10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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{{STRUCTURE_3ckn| PDB=3ckn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ckn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckn OCA], [https://pdbe.org/3ckn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ckn RCSB], [https://www.ebi.ac.uk/pdbsum/3ckn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ckn ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of a Mycobacterial Protein===
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== Function ==
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[https://www.uniprot.org/uniprot/GPGS_MYCPA GPGS_MYCPA] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of UDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG). Although UDP-glucose is the natural donor sugar, GpgS can also use UDP-GalNAc, UDPGlcNAc, UDP-alpha-L-arabinose, UDP-Gal, UDP-Glc, UDP-alpha-Dglucuronic acid, and UDP-alpha-D-xylose as donor substrates.<ref>PMID:18667419</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18667419}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18667419 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3ckn_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18667419}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3CKN is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_avium_subsp._paratuberculosis Mycobacterium avium subsp. paratuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKN OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ckn ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species., Fulton Z, McAlister A, Wilce MC, Brammananth R, Zaker-Tabrizi L, Perugini MA, Bottomley SP, Coppel RL, Crellin PK, Rossjohn J, Beddoe T, J Biol Chem. 2008 Oct 10;283(41):27881-90. Epub 2008 Jul 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18667419 18667419]
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<references/>
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[[Category: Mycobacterium avium subsp. paratuberculosis]]
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__TOC__
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[[Category: Marland, Z.]]
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</StructureSection>
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[[Category: Rossjohn, J.]]
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[[Category: Large Structures]]
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[[Category: Mycobacteria]]
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[[Category: Mycobacterium avium subsp. paratuberculosis K-10]]
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[[Category: Unknown function]]
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[[Category: Marland Z]]
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[[Category: Rossjohn J]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 19 19:57:23 2008''
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Current revision

Crystal Structure of a Mycobacterial Protein

PDB ID 3ckn

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