1ucu

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(New page: 200px<br /><applet load="1ucu" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ucu, resolution 4.0&Aring;" /> '''R-type straight flage...)
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[[Image:1ucu.gif|left|200px]]<br /><applet load="1ucu" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1ucu, resolution 4.0&Aring;" />
 
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'''R-type straight flagellar filament made of full-length flagellin'''<br />
 
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==Overview==
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==R-type straight flagellar filament made of full-length flagellin==
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The bacterial flagellar filament is a helical propeller for bacterial, locomotion. It is a helical assembly of a single protein, flagellin, and, its tubular structure is formed by 11 protofilaments in two distinct, conformations, L- and R-type, for supercoiling. The X-ray crystal, structure of a flagellin fragment lacking about 100 terminal residues, revealed the protofilament structure, but the full filament structure is, still essential for understanding the mechanism of supercoiling and, polymerization. Here we report a complete atomic model of the R-type, filament by electron cryomicroscopy. A density map obtained from image, data up to 4 A resolution shows the feature of alpha-helical backbone and, some large side chains. The atomic model built on the map reveals, intricate molecular packing and an alpha-helical coiled coil formed by the, terminal chains in the inner core of the filament, with its intersubunit, hydrophobic interactions having an important role in stabilizing the, filament.
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<SX load='1ucu' size='340' side='right' viewer='molstar' caption='[[1ucu]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ucu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UCU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ucu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ucu OCA], [https://pdbe.org/1ucu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ucu RCSB], [https://www.ebi.ac.uk/pdbsum/1ucu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ucu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FLIC_SALTY FLIC_SALTY] Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1ucu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ucu ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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1UCU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UCU OCA].
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*[[Flagellin 3D structures|Flagellin 3D structures]]
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__TOC__
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==Reference==
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</SX>
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Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy., Yonekura K, Maki-Yonekura S, Namba K, Nature. 2003 Aug 7;424(6949):643-50. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12904785 12904785]
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[[Category: Large Structures]]
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[[Category: Salmonella typhimurium]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Single protein]]
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[[Category: Maki-Yonekura S]]
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[[Category: Maki-Yonekura, S.]]
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[[Category: Namba K]]
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[[Category: Namba, K.]]
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[[Category: Yonekura K]]
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[[Category: Yonekura, K.]]
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[[Category: cryo-electron microscopy]]
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[[Category: flagellar filament]]
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[[Category: flagellin]]
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[[Category: helical reconstruction]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:01:37 2007''
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Current revision

R-type straight flagellar filament made of full-length flagellin

1ucu, resolution 4.00Å

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