3f2u
From Proteopedia
(Difference between revisions)
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human chromobox homolog 1 (CBX1)== | |
| - | + | <StructureSection load='3f2u' size='340' side='right'caption='[[3f2u]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3f2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F2U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f2u OCA], [https://pdbe.org/3f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f2u RCSB], [https://www.ebi.ac.uk/pdbsum/3f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f2u ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CBX1_HUMAN CBX1_HUMAN] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/3f2u_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f2u ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Amaya MF]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Botchkarev A]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Kozieradzki I]] | ||
| + | [[Category: Loppnau P]] | ||
| + | [[Category: Min J]] | ||
| + | [[Category: Ouyang H]] | ||
| + | [[Category: Ravichandran M]] | ||
| + | [[Category: Tempel W]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Wernimont AK]] | ||
Current revision
Crystal structure of human chromobox homolog 1 (CBX1)
| |||||||||||
Categories: Homo sapiens | Large Structures | Amaya MF | Arrowsmith CH | Botchkarev A | Bountra C | Edwards AM | Kozieradzki I | Loppnau P | Min J | Ouyang H | Ravichandran M | Tempel W | Weigelt J | Wernimont AK
