3epo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:48, 21 February 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3epo.png|left|200px]]
 
-
<!--
+
==Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P==
-
The line below this paragraph, containing "STRUCTURE_3epo", creates the "Structure Box" on the page.
+
<StructureSection load='3epo' size='340' side='right'caption='[[3epo]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3epo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EPO FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MP5:(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL+DIHYDROGEN+PHOSPHATE'>MP5</scene></td></tr>
-
{{STRUCTURE_3epo| PDB=3epo | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3epo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3epo OCA], [https://pdbe.org/3epo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3epo RCSB], [https://www.ebi.ac.uk/pdbsum/3epo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3epo ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/THIC_CAUVC THIC_CAUVC] Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<ref>PMID:18953358</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_18953358}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 18953358 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/3epo_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_18953358}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
3EPO is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EPO OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3epo ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily., Chatterjee A, Li Y, Zhang Y, Grove TL, Lee M, Krebs C, Booker SJ, Begley TP, Ealick SE, Nat Chem Biol. 2008 Dec;4(12):758-65. Epub 2008 Oct 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18953358 18953358]
+
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Caulobacter vibrioides]]
[[Category: Caulobacter vibrioides]]
-
[[Category: Begley, T P.]]
+
[[Category: Large Structures]]
-
[[Category: Booker, S J.]]
+
[[Category: Begley TP]]
-
[[Category: Chatterjee, A.]]
+
[[Category: Booker SJ]]
-
[[Category: Ealick, S E.]]
+
[[Category: Chatterjee A]]
-
[[Category: Grove, T L.]]
+
[[Category: Ealick SE]]
-
[[Category: Krebs, C.]]
+
[[Category: Grove TL]]
-
[[Category: Lee, M.]]
+
[[Category: Krebs C]]
-
[[Category: Li, S.]]
+
[[Category: Lee M]]
-
[[Category: Zhang, Y.]]
+
[[Category: Li S]]
-
[[Category: Alpha-beta barrel]]
+
[[Category: Zhang Y]]
-
[[Category: Biosynthetic protein]]
+
-
[[Category: Sam superfamily]]
+
-
[[Category: Thiamine biosynthesis]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 26 20:11:36 2008''
+

Current revision

Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P

PDB ID 3epo

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3epo"
Personal tools