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3c9z

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{{Seed}}
 
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[[Image:3c9z.jpg|left|200px]]
 
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==Sambucus nigra agglutinin II (SNA-II), tetragonal crystal form==
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The line below this paragraph, containing "STRUCTURE_3c9z", creates the "Structure Box" on the page.
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<StructureSection load='3c9z' size='340' side='right'caption='[[3c9z]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3c9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sambucus_nigra Sambucus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C9Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3c9z| PDB=3c9z | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c9z OCA], [https://pdbe.org/3c9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c9z RCSB], [https://www.ebi.ac.uk/pdbsum/3c9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c9z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NIGB_SAMNI NIGB_SAMNI] Non-toxic type 2 RIP which strongly inhibits mammalian protein synthesis but does not affect plant nor bacterial protein synthesis. The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain is a galactose-specific lectin that facilitates the binding of nigrin b to the cell membrane that precedes endocytosis.
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===Sambucus nigra agglutinin II (SNA-II), tetragonal crystal form===
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==See Also==
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 18798567 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18798567}}
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==About this Structure==
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3C9Z is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sambucus_nigra Sambucus nigra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C9Z OCA].
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==Reference==
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Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra., Maveyraud L, Niwa H, Guillet V, Svergun DI, Konarev PV, Palmer RA, Peumans WJ, Rouge P, Van Damme EJ, Reynolds CD, Mourey L, Proteins. 2008 Sep 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18798567 18798567]
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[[Category: Sambucus nigra]]
[[Category: Sambucus nigra]]
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[[Category: Guillet, V.]]
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[[Category: Guillet V]]
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[[Category: Maveyraud, L.]]
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[[Category: Maveyraud L]]
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[[Category: Mourey, L.]]
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[[Category: Mourey L]]
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[[Category: Beta-trefoil]]
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[[Category: Glycoprotein]]
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[[Category: Glycosylation]]
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[[Category: Lectin]]
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[[Category: Plant protein]]
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[[Category: Ricin-b domain]]
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[[Category: Sugar binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 27 13:34:11 2008''
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Current revision

Sambucus nigra agglutinin II (SNA-II), tetragonal crystal form

PDB ID 3c9z

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