3bo0

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{{Seed}}
 
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[[Image:3bo0.jpg|left|200px]]
 
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==Ribosome-SecY complex==
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The line below this paragraph, containing "STRUCTURE_3bo0", creates the "Structure Box" on the page.
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<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution|resolution]] 9.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [https://pdbe.org/3bo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>
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{{STRUCTURE_3bo0| PDB=3bo0 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bo0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bo0 ConSurf].
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<div style="clear:both"></div>
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===Ribosome-SecY complex===
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==See Also==
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*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
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__TOC__
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</SX>
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The line below this paragraph, {{ABSTRACT_PUBMED_18158904}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18158904 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18158904}}
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==About this Structure==
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3BO0 is a 7 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA].
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==Reference==
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Ribosome binding of a single copy of the SecY complex: implications for protein translocation., Menetret JF, Schaletzky J, Clemons WM Jr, Osborne AR, Skanland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW, Mol Cell. 2007 Dec 28;28(6):1083-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18158904 18158904]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Akey, C W.]]
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[[Category: Large Structures]]
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[[Category: Menetret, J F.]]
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[[Category: Akey CW]]
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[[Category: Protein translocation]]
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[[Category: Menetret JF]]
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[[Category: Ribosome-secy complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:01:17 2008''
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Current revision

Ribosome-SecY complex

3bo0, resolution 9.60Å

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OCA

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