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1v9x
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1v9x" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v9x" /> '''Solution structure of the first Zn-finger do...) |
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| - | [[Image:1v9x.gif|left|200px]]<br /><applet load="1v9x" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1v9x" /> | ||
| - | '''Solution structure of the first Zn-finger domain of poly(ADP-ribose) polymerase-1'''<br /> | ||
| - | == | + | ==Solution structure of the first Zn-finger domain of poly(ADP-ribose) polymerase-1== |
| - | + | <StructureSection load='1v9x' size='340' side='right'caption='[[1v9x]]' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[1v9x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V9X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V9X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v9x OCA], [https://pdbe.org/1v9x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v9x RCSB], [https://www.ebi.ac.uk/pdbsum/1v9x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v9x ProSAT], [https://www.topsan.org/Proteins/RSGI/1v9x TOPSAN]</span></td></tr> | |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PARP1_ARATH PARP1_ARATH] Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity). | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v9x_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v9x ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hayashi F]] | ||
| + | [[Category: Nagashima T]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Solution structure of the first Zn-finger domain of poly(ADP-ribose) polymerase-1
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