1xlr

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{{Seed}}
 
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[[Image:1xlr.png|left|200px]]
 
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==CHORISMATE LYASE WITH INHIBITOR VANILLATE==
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The line below this paragraph, containing "STRUCTURE_1xlr", creates the "Structure Box" on the page.
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<StructureSection load='1xlr' size='340' side='right'caption='[[1xlr]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xlr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XLR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XLR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VNL:4-HYDROXY-3-METHOXYBENZOATE'>VNL</scene></td></tr>
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{{STRUCTURE_1xlr| PDB=1xlr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xlr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xlr OCA], [https://pdbe.org/1xlr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xlr RCSB], [https://www.ebi.ac.uk/pdbsum/1xlr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xlr ProSAT]</span></td></tr>
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</table>
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===CHORISMATE LYASE WITH INHIBITOR VANILLATE===
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== Function ==
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[https://www.uniprot.org/uniprot/UBIC_ECOLI UBIC_ECOLI] Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.[HAMAP-Rule:MF_01632]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16343413}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16343413 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xl/1xlr_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16343413}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1XLR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XLR OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xlr ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural analysis of ligand binding and catalysis in chorismate lyase., Smith N, Roitberg AE, Rivera E, Howard A, Holden MJ, Mayhew M, Kaistha S, Gallagher DT, Arch Biochem Biophys. 2006 Jan 1;445(1):72-80. Epub 2005 Nov 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16343413 16343413]
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Gallagher, D T.]]
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[[Category: Large Structures]]
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[[Category: Smith, N.]]
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[[Category: Gallagher DT]]
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[[Category: Lyase]]
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[[Category: Smith N]]
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[[Category: Mechanism]]
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[[Category: Secondary inhibitor site]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:12:45 2008''
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Current revision

CHORISMATE LYASE WITH INHIBITOR VANILLATE

PDB ID 1xlr

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