2e7d

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{{Seed}}
 
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[[Image:2e7d.png|left|200px]]
 
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==Crystal structure of a NEAT domain from Staphylococcus aureus==
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The line below this paragraph, containing "STRUCTURE_2e7d", creates the "Structure Box" on the page.
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<StructureSection load='2e7d' size='340' side='right'caption='[[2e7d]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2e7d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E7D FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2e7d| PDB=2e7d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e7d OCA], [https://pdbe.org/2e7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e7d RCSB], [https://www.ebi.ac.uk/pdbsum/2e7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e7d ProSAT]</span></td></tr>
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</table>
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===Crystal structure of a NEAT domain from Staphylococcus aureus===
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== Function ==
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[https://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18667422 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/2e7d_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18667422}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2E7D is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7D OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e7d ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structural basis for multimeric heme complexation through a specific protein-heme interaction: the case of the third neat domain of IsdH from Staphylococcus aureus., Watanabe M, Tanaka Y, Suenaga A, Kuroda M, Yao M, Watanabe N, Arisaka F, Ohta T, Tanaka I, Tsumoto K, J Biol Chem. 2008 Oct 17;283(42):28649-59. Epub 2008 Jul 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18667422 18667422]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Kumagai, I.]]
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[[Category: Kumagai I]]
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[[Category: Suenaga, A.]]
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[[Category: Suenaga A]]
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[[Category: Tanaka, I.]]
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[[Category: Tanaka I]]
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[[Category: Tanaka, Y.]]
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[[Category: Tanaka Y]]
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[[Category: Tsumoto, K.]]
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[[Category: Tsumoto K]]
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[[Category: Yao, M.]]
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[[Category: Yao M]]
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[[Category: Ig-like fold]]
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[[Category: Metal binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:14:44 2008''
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Current revision

Crystal structure of a NEAT domain from Staphylococcus aureus

PDB ID 2e7d

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