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3e25

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{{Seed}}
 
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[[Image:3e25.png|left|200px]]
 
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==Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase==
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The line below this paragraph, containing "STRUCTURE_3e25", creates the "Structure Box" on the page.
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<StructureSection load='3e25' size='340' side='right'caption='[[3e25]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3e25]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E25 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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{{STRUCTURE_3e25| PDB=3e25 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e25 OCA], [https://pdbe.org/3e25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e25 RCSB], [https://www.ebi.ac.uk/pdbsum/3e25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e25 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase===
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== Function ==
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[https://www.uniprot.org/uniprot/GPGS_MYCTU GPGS_MYCTU] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of NDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG).<ref>PMID:22637481</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_19015727}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19015727 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e25_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19015727}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3E25 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E25 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e25 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis., Pereira PJ, Empadinhas N, Albuquerque L, Sa-Moura B, da Costa MS, Macedo-Ribeiro S, PLoS ONE. 2008;3(11):e3748. Epub 2008 Nov 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19015727 19015727]
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<references/>
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__TOC__
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Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase., Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS, FEMS Microbiol Lett. 2008 Mar;280(2):195-202. Epub 2008 Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18221489 18221489]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Costa, M S.]]
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[[Category: Costa MS]]
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[[Category: Empadinhas, N.]]
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[[Category: Empadinhas N]]
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[[Category: Macedo-Ribeiro, S.]]
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[[Category: Macedo-Ribeiro S]]
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[[Category: Pereira, P J.B.]]
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[[Category: Pereira PJB]]
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[[Category: 3-phosphoglycerate]]
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[[Category: Glucosyltransferase]]
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[[Category: Gt81 udp-glucose]]
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[[Category: Mycobacterial]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:26:29 2008''
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Current revision

Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase

PDB ID 3e25

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