2zuv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:58, 13 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2zuv.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of Galacto-N-biose/Lacto-N-biose I phosphorylase in complex with GlcNAc, Ethylene glycol, and nitrate==
-
The line below this paragraph, containing "STRUCTURE_2zuv", creates the "Structure Box" on the page.
+
<StructureSection load='2zuv' size='340' side='right'caption='[[2zuv]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2zuv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bifidobacterium_longum Bifidobacterium longum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZUV FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-
{{STRUCTURE_2zuv| PDB=2zuv | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuv OCA], [https://pdbe.org/2zuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zuv RCSB], [https://www.ebi.ac.uk/pdbsum/2zuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuv ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of Galacto-N-biose/Lacto-N-biose I phosphorylase in complex with GlcNAc, Ethylene glycol, and nitrate===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/LNPA_BIFL2 LNPA_BIFL2] Reversibly phosphorolyzes lacto-N-biose to Gal1-P and N-acetylglucosamine (GlcNAc) and galacto-N-biose to Gal1-P and N-acetylgalactosamine (GalNAc). Involved in the lacto-N-biose I/galacto-N-biose (LNB/GNB) degradation pathway, which is important for host intestinal colonization by bifidobacteria.<ref>PMID:15933016</ref> <ref>PMID:17720833</ref> <ref>PMID:19124470</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15933016}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15933016 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zuv_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15933016}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
2ZUV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bifidobacterium_longum Bifidobacterium longum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUV OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zuv ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
Novel putative galactose operon involving lacto-N-biose phosphorylase in Bifidobacterium longum., Kitaoka M, Tian J, Nishimoto M, Appl Environ Microbiol. 2005 Jun;71(6):3158-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15933016 15933016]
+
<references/>
-
[[Category: 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase]]
+
__TOC__
 +
</StructureSection>
[[Category: Bifidobacterium longum]]
[[Category: Bifidobacterium longum]]
-
[[Category: Fushinobu, S.]]
+
[[Category: Large Structures]]
-
[[Category: Hidaka, M.]]
+
[[Category: Fushinobu S]]
-
[[Category: Kitaoka, M.]]
+
[[Category: Hidaka M]]
-
[[Category: Nishimoto, M.]]
+
[[Category: Kitaoka M]]
-
[[Category: Shoun, H.]]
+
[[Category: Nishimoto M]]
-
[[Category: Wakagi, T.]]
+
[[Category: Shoun H]]
-
[[Category: Beta-alpha-barrel]]
+
[[Category: Wakagi T]]
-
[[Category: Glycosyltransferase]]
+
-
[[Category: Tim barrel]]
+
-
[[Category: Transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 10:12:48 2008''
+

Current revision

Crystal structure of Galacto-N-biose/Lacto-N-biose I phosphorylase in complex with GlcNAc, Ethylene glycol, and nitrate

PDB ID 2zuv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools