3e2y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:57, 30 August 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3e2y.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of mouse kynurenine aminotransferase III in complex with glutamine==
-
The line below this paragraph, containing "STRUCTURE_3e2y", creates the "Structure Box" on the page.
+
<StructureSection load='3e2y' size='340' side='right'caption='[[3e2y]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3e2y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E2Y FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
-
{{STRUCTURE_3e2y| PDB=3e2y | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e2y OCA], [https://pdbe.org/3e2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e2y RCSB], [https://www.ebi.ac.uk/pdbsum/3e2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e2y ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of mouse kynurenine aminotransferase III in complex with glutamine===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/KAT3_MOUSE KAT3_MOUSE] Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).<ref>PMID:19029248</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_19029248}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 19029248 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e2y_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_19029248}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
3E2Y is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2Y OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e2y ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
Biochemical and structural properties of mouse KAT III., Han Q, Robinson H, Cai T, Tagle DA, Li J, Mol Cell Biol. 2008 Nov 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19029248 19029248]
+
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Cai, T.]]
+
[[Category: Cai T]]
-
[[Category: Han, Q.]]
+
[[Category: Han Q]]
-
[[Category: Li, J.]]
+
[[Category: Li J]]
-
[[Category: Robinson, R.]]
+
[[Category: Robinson R]]
-
[[Category: Tagle, D A.]]
+
[[Category: Tagle DA]]
-
[[Category: Alpha beta protein]]
+
-
[[Category: Alternative splicing]]
+
-
[[Category: Aminotransferase]]
+
-
[[Category: Lyase]]
+
-
[[Category: Plp dependent protein]]
+
-
[[Category: Pyridoxal phosphate]]
+
-
[[Category: Transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 10:29:57 2008''
+

Current revision

Crystal structure of mouse kynurenine aminotransferase III in complex with glutamine

PDB ID 3e2y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3e2y"
Personal tools