3c6a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:33, 21 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3c6a.jpg|left|200px]]
 
-
<!--
+
==Crystal Structure of the RB49 gp17 nuclease domain==
-
The line below this paragraph, containing "STRUCTURE_3c6a", creates the "Structure Box" on the page.
+
<StructureSection load='3c6a' size='340' side='right'caption='[[3c6a]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3c6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB49 Escherichia phage RB49]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C6A FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_3c6a| PDB=3c6a | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c6a OCA], [https://pdbe.org/3c6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c6a RCSB], [https://www.ebi.ac.uk/pdbsum/3c6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c6a ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9T1C3_BPRB4 Q9T1C3_BPRB4] The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer. Once the capsid is packaged with the DNA, the terminase complex is substituted by the tail.[HAMAP-Rule:MF_04146]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c6/3c6a_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c6a ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal Structure of the RB49 gp17 nuclease domain===
+
==See Also==
-
 
+
*[[Terminase 3D Structures|Terminase 3D Structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_19109896}}, adds the Publication Abstract to the page
+
[[Category: Escherichia phage RB49]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 19109896 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
[[Category: Rossmann MG]]
-
{{ABSTRACT_PUBMED_19109896}}
+
[[Category: Sun S]]
-
 
+
-
==About this Structure==
+
-
3C6A is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb49 Enterobacteria phage rb49]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6A OCA].
+
-
 
+
-
==Reference==
+
-
The structure of the phage T4 DNA packaging motor suggests a mechanism dependent on electrostatic forces., Sun S, Kondabagil K, Draper B, Alam TI, Bowman VD, Zhang Z, Hegde S, Fokine A, Rossmann MG, Rao VB, Cell. 2008 Dec 26;135(7):1251-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19109896 19109896]
+
-
[[Category: Enterobacteria phage rb49]]
+
-
[[Category: Rossmann, M G.]]
+
-
[[Category: Sun, S.]]
+
-
[[Category: Terminase nuclease]]
+
-
[[Category: Viral protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 13:12:26 2009''
+

Current revision

Crystal Structure of the RB49 gp17 nuclease domain

PDB ID 3c6a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3c6a"
Personal tools