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3ezy

From Proteopedia

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{{Seed}}
 
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[[Image:3ezy.jpg|left|200px]]
 
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==Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima==
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The line below this paragraph, containing "STRUCTURE_3ezy", creates the "Structure Box" on the page.
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<StructureSection load='3ezy' size='340' side='right'caption='[[3ezy]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ezy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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{{STRUCTURE_3ezy| PDB=3ezy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ezy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezy OCA], [https://pdbe.org/3ezy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ezy RCSB], [https://www.ebi.ac.uk/pdbsum/3ezy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezy ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ezy TOPSAN]</span></td></tr>
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</table>
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===Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima===
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== Function ==
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[https://www.uniprot.org/uniprot/IOLG_THEMA IOLG_THEMA] Catalyzes the NAD(+)-dependent oxidation of myo-inositol (MI) to 2-keto-myo-inositol (scyllo-inosose), and thus probably functions in a myo-inositol degradation pathway together with IolM, IolN and IolO. Has no activity with scyllo-inositol and much reduced activity (78-fold lower catalytic efficiency) with 1D-chiro-inositol.<ref>PMID:23441918</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3EZY is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZY OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/3ezy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ezy ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Chang, S.]]
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[[Category: Chang S]]
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[[Category: Freeman, J.]]
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[[Category: Freeman J]]
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[[Category: Gheyi, T.]]
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[[Category: Gheyi T]]
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[[Category: Maletic, M.]]
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[[Category: Maletic M]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Ramagopal UA]]
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[[Category: Ramagopal, U A.]]
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[[Category: Toro R]]
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[[Category: Toro, R.]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 13:35:04 2009''
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Current revision

Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima

PDB ID 3ezy

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