3ftj
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3ftj is ON HOLD Authors: Xu, Y., Sim, S.H., Jin, X.L., Kim, H.M., Jeong, M.H., Lee, K., Ha, N.C. Description: Crystal structure of the periplasmic ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans== | |
| - | + | <StructureSection load='3ftj' size='340' side='right'caption='[[3ftj]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ftj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.999Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ftj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ftj OCA], [https://pdbe.org/3ftj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ftj RCSB], [https://www.ebi.ac.uk/pdbsum/3ftj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ftj ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MACB_AGGAC MACB_AGGAC] Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.<ref>PMID:19432486</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/3ftj_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ftj ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aggregatibacter actinomycetemcomitans]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ha NC]] | ||
| + | [[Category: Xu Y]] | ||
Current revision
Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans
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