3d0t

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{{Seed}}
 
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[[Image:3d0t.png|left|200px]]
 
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==Structure of the BNB domain of the Hsp70 cochaperone Bag2==
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The line below this paragraph, containing "STRUCTURE_3d0t", creates the "Structure Box" on the page.
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<StructureSection load='3d0t' size='340' side='right'caption='[[3d0t]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3d0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D0T FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d0t OCA], [https://pdbe.org/3d0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d0t RCSB], [https://www.ebi.ac.uk/pdbsum/3d0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d0t ProSAT]</span></td></tr>
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{{STRUCTURE_3d0t| PDB=3d0t | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BAG2_MOUSE BAG2_MOUSE] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d0/3d0t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d0t ConSurf].
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<div style="clear:both"></div>
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===Structure of the BNB domain of the Hsp70 cochaperone Bag2===
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==See Also==
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*[[BAG family proteins 3D structures|BAG family proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_19029896}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 19029896 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19029896}}
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==About this Structure==
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3D0T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D0T OCA].
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==Reference==
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Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2., Xu Z, Page RC, Gomes MM, Kohli E, Nix JC, Herr AB, Patterson C, Misra S, Nat Struct Mol Biol. 2008 Dec;15(12):1309-17. Epub 2008 Nov 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19029896 19029896]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Devlin K]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Misra S]]
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[[Category: 4-helix bundle]]
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[[Category: Nix JC]]
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[[Category: Chaperone]]
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[[Category: Xu Z]]
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[[Category: Coiled coil]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 20:24:15 2009''
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Current revision

Structure of the BNB domain of the Hsp70 cochaperone Bag2

PDB ID 3d0t

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