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3f0o

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{{Seed}}
 
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[[Image:3f0o.png|left|200px]]
 
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==Crystal structure of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system==
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The line below this paragraph, containing "STRUCTURE_3f0o", creates the "Structure Box" on the page.
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<StructureSection load='3f0o' size='340' side='right'caption='[[3f0o]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3f0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F0O FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr>
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{{STRUCTURE_3f0o| PDB=3f0o | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f0o OCA], [https://pdbe.org/3f0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f0o RCSB], [https://www.ebi.ac.uk/pdbsum/3f0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f0o ProSAT]</span></td></tr>
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</table>
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===Crystal structure of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system===
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== Function ==
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[https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_19004822}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19004822 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/3f0o_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19004822}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3F0O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F0O OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f0o ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION., Lafrance-Vanasse J, Lefebvre M, Di Lello P, Sygusch J, Omichinski JG, J Biol Chem. 2009 Jan 9;284(2):938-44. Epub 2008 Nov 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19004822 19004822]
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</StructureSection>
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[[Category: Alkylmercury lyase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Di Lello P]]
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[[Category: Alkylmercury lyase]]
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[[Category: Lafrance-Vanasse J]]
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[[Category: Merb]]
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[[Category: Lefebvre M]]
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[[Category: Mercuric resistance]]
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[[Category: Omichinski JG]]
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[[Category: Mercury resistance]]
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[[Category: Sygusch J]]
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[[Category: Organomercurial lyase]]
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[[Category: Plasmid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 20:34:29 2009''
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Current revision

Crystal structure of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system

PDB ID 3f0o

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