This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wkj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1wkj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wkj, resolution 2.0&Aring;" /> '''Crystal Structure of ...)
Current revision (07:56, 25 October 2023) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1wkj.gif|left|200px]]<br /><applet load="1wkj" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1wkj, resolution 2.0&Aring;" />
 
-
'''Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8'''<br />
 
-
==About this Structure==
+
==Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8==
-
1WKJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Active as [http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WKJ OCA].
+
<StructureSection load='1wkj' size='340' side='right'caption='[[1wkj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
[[Category: Nucleoside-diphosphate kinase]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[1wkj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKJ FirstGlance]. <br>
-
[[Category: Thermus thermophilus]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
[[Category: Kuramitsu, S.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkj OCA], [https://pdbe.org/1wkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkj RCSB], [https://www.ebi.ac.uk/pdbsum/1wkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkj ProSAT], [https://www.topsan.org/Proteins/RSGI/1wkj TOPSAN]</span></td></tr>
-
[[Category: Masui, R.]]
+
</table>
-
[[Category: Nakagawa, N.]]
+
== Function ==
-
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+
[https://www.uniprot.org/uniprot/NDK_THET8 NDK_THET8] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
-
[[Category: Takeishi, S.]]
+
== Evolutionary Conservation ==
-
[[Category: kinase]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: nucleoside diphosphate kinase]]
+
Check<jmol>
-
[[Category: riken structural genomics/proteomics initiative]]
+
<jmolCheckbox>
-
[[Category: rsgi]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkj_consurf.spt"</scriptWhenChecked>
-
[[Category: structural genomics]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: thermus thermophilus hb8]]
+
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkj ConSurf].
 +
<div style="clear:both"></div>
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 05:29:27 2007''
+
==See Also==
 +
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Thermus thermophilus]]
 +
[[Category: Kuramitsu S]]
 +
[[Category: Masui R]]
 +
[[Category: Nakagawa N]]
 +
[[Category: Takeishi S]]

Current revision

Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8

PDB ID 1wkj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools