3fpx

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{{Seed}}
 
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[[Image:3fpx.jpg|left|200px]]
 
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==Native fungus laccase from Trametes hirsuta==
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The line below this paragraph, containing "STRUCTURE_3fpx", creates the "Structure Box" on the page.
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<StructureSection load='3fpx' size='340' side='right'caption='[[3fpx]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3fpx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trametes_hirsuta Trametes hirsuta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FPX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3fpx| PDB=3fpx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fpx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fpx OCA], [https://pdbe.org/3fpx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fpx RCSB], [https://www.ebi.ac.uk/pdbsum/3fpx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fpx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B2L9C1_TRAHI B2L9C1_TRAHI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/3fpx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fpx ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Laccase from the fungus Coriolus hirsutus has been purified. Crystals of the enzyme suitable for X-ray structure analysis have been obtained under optimized crystallization conditions using polyethylene glycol as a precipitant. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 50.65, b = 74.01, c = 124.83 A, and contain 40% solvent and a single molecule of laccase in the asymmetric unit. X-ray data were collected to 1.85 A at the copper edge and the four copper sites have been located from the anomalous signal. The obtained SAD phases with subsequent density modification produced a promising initial electron-density map.
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===Native fungus laccase from Trametes hirsuta===
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Crystallization and preliminary X-ray analysis of a four-copper laccase from Coriolus hirsutus.,Pegasova TV, Zwart P, Koroleva OV, Stepanova EV, Rebrikov DV, Lamzin VS Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1459-61. Epub 2003, Jul 23. PMID:012876350<ref>PMID:012876350</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3fpx" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_12876350}}, adds the Publication Abstract to the page
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*[[Laccase 3D structures|Laccase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12876350 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_12876350}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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3FPX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Trametes_hirsuta Trametes hirsuta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPX OCA].
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==Reference==
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Crystallization and preliminary X-ray analysis of a four-copper laccase from Coriolus hirsutus., Pegasova TV, Zwart P, Koroleva OV, Stepanova EV, Rebrikov DV, Lamzin VS, Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1459-61. Epub 2003, Jul 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12876350 12876350]
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[[Category: Laccase]]
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[[Category: Single protein]]
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[[Category: Trametes hirsuta]]
[[Category: Trametes hirsuta]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Cherkashin EA]]
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[[Category: 4-copper protein]]
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[[Category: Fedorova TV]]
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[[Category: Beta sheet]]
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[[Category: Koroleva OV]]
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[[Category: Copper]]
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[[Category: Kurzeev SA]]
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[[Category: Metal-binding]]
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[[Category: Lamzin VS]]
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[[Category: Oxidoreductase]]
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[[Category: Polyakov KM]]
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[[Category: Stepanova EV]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 20:23:59 2009''
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[[Category: Strokopytov BV]]

Current revision

Native fungus laccase from Trametes hirsuta

PDB ID 3fpx

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