2zj2

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{{Seed}}
 
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[[Image:2zj2.jpg|left|200px]]
 
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==Archaeal DNA helicase Hjm apo state in form 1==
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The line below this paragraph, containing "STRUCTURE_2zj2", creates the "Structure Box" on the page.
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<StructureSection load='2zj2' size='340' side='right'caption='[[2zj2]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2zj2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZJ2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2zj2| PDB=2zj2 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zj2 OCA], [https://pdbe.org/2zj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zj2 RCSB], [https://www.ebi.ac.uk/pdbsum/2zj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zj2 ProSAT]</span></td></tr>
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</table>
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===Archaeal DNA helicase Hjm apo state in form 1===
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== Function ==
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[https://www.uniprot.org/uniprot/HELS_PYRFU HELS_PYRFU] DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Unwinds the lagging strand from forked DNA structures in a 3'-5' direction. PCNA, the DNA polymerase sliding clamp subunit, stimulates the helicase activity, and may alter substrate specificity. Unwinds branched DNA (Holliday junctions) in an ATP-dependent fashion; ss- and dsDNA stimulate ATPase to the greatest extent, although it preferentially binds DNA with a single-stranded region. Processes a RecA-mediated recombination intermediate between gapped circular and homologus linear dsDNA.<ref>PMID:15677450</ref> <ref>PMID:16436047</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_19159486}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19159486 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zj/2zj2_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19159486}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2ZJ2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJ2 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zj2 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:19159486</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Fujikane, R.]]
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[[Category: Fujikane R]]
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[[Category: Ishino, Y.]]
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[[Category: Ishino Y]]
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[[Category: Morikawa, K.]]
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[[Category: Morikawa K]]
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[[Category: Oka, H.]]
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[[Category: Oka H]]
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[[Category: Oyama, T.]]
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[[Category: Oyama T]]
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[[Category: Atp-binding]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide-binding]]
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[[Category: Reca fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:38:34 2009''
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Current revision

Archaeal DNA helicase Hjm apo state in form 1

PDB ID 2zj2

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