3cp7

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{{Seed}}
 
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[[Image:3cp7.jpg|left|200px]]
 
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==Crystal structure of a thermostable serine protease AL20 from extremophilic microoganism==
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The line below this paragraph, containing "STRUCTURE_3cp7", creates the "Structure Box" on the page.
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<StructureSection load='3cp7' size='340' side='right'caption='[[3cp7]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cp7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nesterenkonia_aethiopica Nesterenkonia aethiopica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CP7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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{{STRUCTURE_3cp7| PDB=3cp7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cp7 OCA], [https://pdbe.org/3cp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cp7 RCSB], [https://www.ebi.ac.uk/pdbsum/3cp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cp7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0VWT7_9MICC D0VWT7_9MICC]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cp/3cp7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cp7 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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A novel calcium-independent serine protease from an alkaliphilic bacterium, Nesterenkonia sp. AL20, has been purified and crystallized at 296 K using sodium formate as the main precipitant. This enzyme is optimally active at pH 10, exhibits high stability towards autolytic digestion and its stability is not affected by the presence of EDTA or detergents. The triangular prism-shaped crystals diffracted X-rays to beyond 1.5 A at a synchrotron beamline, with space group R3 and unit-cell parameters a = b = 92.26, c = 137.88 A. A complete data set has been collected to 1.39 A resolution. The asymmetric unit is estimated and confirmed by self-rotation function calculation to contain two molecules, giving a crystal Volume per protein mass (V(M)) of 2.68 A(3) Da(-1) and a solvent content of 54%.
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===Crystal structure of a thermostable serine protease AL20 from extremophilic microoganism===
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Crystallization and preliminary X-ray analysis of an alkaline serine protease from Nesterenkonia sp.,Bakhtiar S, Vevodova J, Hatti-Kaul R, Su XD Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):529-31. Epub 2003, Feb 21. PMID:012595716<ref>PMID:012595716</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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3CP7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Nesterenkonia_aethiopica Nesterenkonia aethiopica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CP7 OCA].
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<div class="pdbe-citations 3cp7" style="background-color:#fffaf0;"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:18814301</ref><ref group="xtra">PMID:12595716</ref><references group="xtra"/>
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__TOC__
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[[Category: Chymotrypsin]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Nesterenkonia aethiopica]]
[[Category: Nesterenkonia aethiopica]]
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[[Category: Nan, J.]]
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[[Category: Nan J]]
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[[Category: Su, X D.]]
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[[Category: Su X-D]]
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[[Category: Yang, N.]]
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[[Category: Yang N]]
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[[Category: Hydrolase]]
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[[Category: Trypsin-like]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:40:09 2009''
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Current revision

Crystal structure of a thermostable serine protease AL20 from extremophilic microoganism

PDB ID 3cp7

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