2w8h

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{{Seed}}
 
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[[Image:2w8h.jpg|left|200px]]
 
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==Crystal structure of spin labeled Wza24-345.==
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The line below this paragraph, containing "STRUCTURE_2w8h", creates the "Structure Box" on the page.
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<StructureSection load='2w8h' size='340' side='right'caption='[[2w8h]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2w8h]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W8H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MTN:S-[(1-OXYL-2,2,5,5-TETRAMETHYL-2,5-DIHYDRO-1H-PYRROL-3-YL)METHYL]+METHANESULFONOTHIOATE'>MTN</scene></td></tr>
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{{STRUCTURE_2w8h| PDB=2w8h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w8h OCA], [https://pdbe.org/2w8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w8h RCSB], [https://www.ebi.ac.uk/pdbsum/2w8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w8h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X4B7_ECOLX Q9X4B7_ECOLX]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w8/2w8h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w8h ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Distance fingerprinting: Pulsed electron-electron double resonance spectroscopy (PELDOR) is applied to the octameric membrane protein complex Wza of E. coli. The data yielded a detailed distance fingerprint of its periplasmic region that compares favorably to the crystal structure. These results provide the foundation to study conformation changes from interaction with partner proteins.
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===CRYSTAL STRUCTURE OF SPIN LABELED WZA24-345.===
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PELDOR Spectroscopy Distance Fingerprinting of the Octameric Outer-Membrane Protein Wza from Escherichia coli.,Hagelueken G, Ingledew WJ, Huang H, Petrovic-Stojanovska B, Whitfield C, Elmkami H, Schiemann O, Naismith JH Angew Chem Int Ed Engl. 2009 Mar 17;48(16):2904-2906. PMID:19294709<ref>PMID:19294709</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2W8H is a 16 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8H OCA].
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<div class="pdbe-citations 2w8h" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Elmkami, H.]]
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[[Category: Large Structures]]
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[[Category: Hagelueken, G.]]
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[[Category: ElMkami H]]
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[[Category: Huang, H.]]
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[[Category: Hagelueken G]]
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[[Category: Ingledew, W J.]]
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[[Category: Huang H]]
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[[Category: Naismith, J H.]]
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[[Category: Ingledew WJ]]
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[[Category: Petrovic-Stojanovska, B.]]
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[[Category: Naismith JH]]
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[[Category: Schiemann, O.]]
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[[Category: Petrovic-Stojanovska B]]
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[[Category: Whitfield, C.]]
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[[Category: Schiemann O]]
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[[Category: Lipoprotein]]
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[[Category: Whitfield C]]
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[[Category: Membrane protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 14:24:45 2009''
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Current revision

Crystal structure of spin labeled Wza24-345.

PDB ID 2w8h

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