3dgp

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{{Seed}}
 
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[[Image:3dgp.png|left|200px]]
 
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==Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2==
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The line below this paragraph, containing "STRUCTURE_3dgp", creates the "Structure Box" on the page.
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<StructureSection load='3dgp' size='340' side='right'caption='[[3dgp]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3dgp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DGP FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgp OCA], [https://pdbe.org/3dgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dgp RCSB], [https://www.ebi.ac.uk/pdbsum/3dgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dgp ProSAT]</span></td></tr>
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{{STRUCTURE_3dgp| PDB=3dgp | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2===
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[https://www.uniprot.org/uniprot/TFB2_YEAST TFB2_YEAST] Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.<ref>PMID:9235928</ref> <ref>PMID:7961739</ref> <ref>PMID:8631896</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_19172752}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 19172752 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/3dgp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_19172752}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dgp ConSurf].
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3DGP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGP OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:19172752</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cavarelli, J.]]
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[[Category: Cavarelli J]]
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[[Category: Egly, J M.]]
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[[Category: Egly JM]]
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[[Category: Kainov, D E.]]
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[[Category: Kainov DE]]
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[[Category: Poterszman, A.]]
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[[Category: Poterszman A]]
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[[Category: Beta-alpha-beta spilt]]
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[[Category: Dna damage]]
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[[Category: Dna excision]]
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[[Category: Dna repair]]
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[[Category: Heterodimer]]
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[[Category: Nucleus]]
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[[Category: Protein-protein complex]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 15 08:47:25 2009''
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Current revision

Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2

PDB ID 3dgp

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OCA

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