1yiv

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{{Seed}}
 
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[[Image:1yiv.png|left|200px]]
 
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==Structure of myelin P2 protein from Equine spinal cord==
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The line below this paragraph, containing "STRUCTURE_1yiv", creates the "Structure Box" on the page.
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<StructureSection load='1yiv' size='340' side='right'caption='[[1yiv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yiv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YIV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene></td></tr>
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{{STRUCTURE_1yiv| PDB=1yiv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yiv OCA], [https://pdbe.org/1yiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yiv RCSB], [https://www.ebi.ac.uk/pdbsum/1yiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yiv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MYP2_HORSE MYP2_HORSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yiv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yiv ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Equine P2 protein has been isolated from horse spinal cord and its structure determined to 2.1 A. Since equine myelin is a viable alternative to bovine tissue for large-scale preparations, characterization of the proteins from equine spinal cord myelin has been initiated. There is an unusually high amount of P2 protein in equine CNS myelin compared with other species. The structure was determined by molecular replacement and subsequently refined to an R value of 0.187 (Rfree=0.233). The structure contains a molecule of the detergent LDAO and HEPES buffer in the binding cavity and is otherwise analogous to other cellular retinol-binding proteins.
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===Structure of myelin P2 protein from Equine spinal cord===
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Structure of myelin P2 protein from equine spinal cord.,Hunter DJ, Macmaster R, Roszak AW, Riboldi-Tunnicliffe A, Griffiths IR, Freer AA Acta Crystallogr D Biol Crystallogr. 2005 Aug;61(Pt 8):1067-71. Epub 2005, Jul 20. PMID:16041071<ref>PMID:16041071</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_16041071}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1yiv" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 16041071 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_16041071}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1YIV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIV OCA].
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==Reference==
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<ref group="xtra">PMID:16041071</ref><references group="xtra"/>
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[[Category: Equus caballus]]
[[Category: Equus caballus]]
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[[Category: Freer, A A.]]
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[[Category: Large Structures]]
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[[Category: Grifiths, I R.]]
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[[Category: Freer AA]]
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[[Category: Hunter, D J.B.]]
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[[Category: Grifiths IR]]
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[[Category: MacMaster, R.]]
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[[Category: Hunter DJB]]
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[[Category: Riboldi-Tunnicliffe, A.]]
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[[Category: MacMaster R]]
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[[Category: Rozak, A W.]]
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[[Category: Riboldi-Tunnicliffe A]]
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[[Category: P2 protein]]
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[[Category: Rozak AW]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:11:55 2009''
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Current revision

Structure of myelin P2 protein from Equine spinal cord

PDB ID 1yiv

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