2fl7
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2fl7.png|left|200px]] | ||
| - | + | ==S. cerevisiae Sir3 BAH domain== | |
| - | + | <StructureSection load='2fl7' size='340' side='right'caption='[[2fl7]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2fl7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FL7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fl7 OCA], [https://pdbe.org/2fl7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fl7 RCSB], [https://www.ebi.ac.uk/pdbsum/2fl7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fl7 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/SIR3_YEAST SIR3_YEAST] The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | < | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/2fl7_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fl7 ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | < | + | [[Category: Large Structures]] |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Daner | + | [[Category: Daner JR]] |
| - | [[Category: Fox | + | [[Category: Fox CA]] |
| - | [[Category: Hou | + | [[Category: Hou Z]] |
| - | [[Category: Keck | + | [[Category: Keck JL]] |
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Current revision
S. cerevisiae Sir3 BAH domain
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