2r8u

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{{Seed}}
 
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[[Image:2r8u.png|left|200px]]
 
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==Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution==
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The line below this paragraph, containing "STRUCTURE_2r8u", creates the "Structure Box" on the page.
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<StructureSection load='2r8u' size='340' side='right'caption='[[2r8u]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2r8u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R8U FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MOO:MOLYBDATE+ION'>MOO</scene></td></tr>
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{{STRUCTURE_2r8u| PDB=2r8u | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8u OCA], [https://pdbe.org/2r8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r8u RCSB], [https://www.ebi.ac.uk/pdbsum/2r8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r8u_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r8u ConSurf].
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<div style="clear:both"></div>
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===Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution===
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==See Also==
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*[[End-binding protein|End-binding protein]]
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*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]]
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==About this Structure==
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== References ==
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2R8U is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8U OCA].
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Huang, X.]]
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[[Category: Large Structures]]
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[[Category: Lebioda, L.]]
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[[Category: Huang X]]
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[[Category: Lovelace, L L.]]
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[[Category: Lebioda L]]
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[[Category: Smith, D.]]
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[[Category: Lovelace LL]]
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[[Category: Acetylation]]
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[[Category: Smith D]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Cytoplasm]]
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[[Category: Cytoskeleton]]
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[[Category: Microtubule]]
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[[Category: Mitosis]]
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[[Category: Phosphorylation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:23:26 2009''
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Current revision

Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution

PDB ID 2r8u

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