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2f5u

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{{Seed}}
 
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[[Image:2f5u.png|left|200px]]
 
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==Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus Type 1==
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The line below this paragraph, containing "STRUCTURE_2f5u", creates the "Structure Box" on the page.
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<StructureSection load='2f5u' size='340' side='right'caption='[[2f5u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2f5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F5U FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f5u OCA], [https://pdbe.org/2f5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f5u RCSB], [https://www.ebi.ac.uk/pdbsum/2f5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f5u ProSAT]</span></td></tr>
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{{STRUCTURE_2f5u| PDB=2f5u | SCENE= }}
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</table>
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== Function ==
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===Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus Type 1===
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[https://www.uniprot.org/uniprot/CVC2_HHV11 CVC2_HHV11] Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP. May mediate the capsid docking to the nuclear pore allowing entry of the viral genome into the host nucleus through binding to host nucleoporins NUP214.[HAMAP-Rule:MF_04025]<ref>PMID:18448531</ref> <ref>PMID:18945788</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16474137}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16474137 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/2f5u_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16474137}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f5u ConSurf].
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2F5U is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1 Human herpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F5U OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:16474137</ref><references group="xtra"/>
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__TOC__
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[[Category: Human herpesvirus 1]]
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</StructureSection>
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[[Category: Bowman, B R.]]
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[[Category: Human alphaherpesvirus 1]]
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[[Category: Capsid protein]]
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[[Category: Large Structures]]
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[[Category: Dna packaging]]
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[[Category: Bowman BR]]
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[[Category: Head completion]]
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[[Category: Hsv-1]]
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[[Category: Ul25]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:49:58 2009''
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Current revision

Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus Type 1

PDB ID 2f5u

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