1urr

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{{Seed}}
 
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[[Image:1urr.png|left|200px]]
 
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==A novel Drosophila Melanogaster Acylphosphatase (AcPDro2)==
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The line below this paragraph, containing "STRUCTURE_1urr", creates the "Structure Box" on the page.
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<StructureSection load='1urr' size='340' side='right'caption='[[1urr]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1urr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1URR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_1urr| PDB=1urr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1urr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1urr OCA], [https://pdbe.org/1urr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1urr RCSB], [https://www.ebi.ac.uk/pdbsum/1urr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1urr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACYP2_DROME ACYP2_DROME]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ur/1urr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1urr ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Analysis of the Drosophila melanogaster EST database led to the discovery and cloning of a novel acylphosphatase. The CG18505 gene coding for a new enzyme (AcPDro2) is clearly distinct from the previously described CG16870Acyp gene, which also codes for a D. melanogaster acylphosphatase (AcPDro). The putative catalytic residues, together with residues held to stabilize the acylphosphatase fold, are conserved in the two encoded proteins. Crystals of AcPDro2, which belong to the trigonal space group P3(1)21, with unit-cell parameters a = b = 45.8, c = 98.6 angstroms, gamma = 120 degrees, allowed the solution of the protein structure by molecular replacement and its refinement to 1.5 angstroms resolution. The AcPDro2 active-site structure is discussed.
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===A NOVEL DROSOPHILA MELANOGASTER ACYLPHOSPHATASE (ACPDRO2)===
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Three-dimensional structural characterization of a novel Drosophila melanogaster acylphosphatase.,Zuccotti S, Rosano C, Ramazzotti M, Degl'Innocenti D, Stefani M, Manao G, Bolognesi M Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1177-9. Epub 2004, May 21. PMID:15159593<ref>PMID:15159593</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_15159593}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1urr" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15159593 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15159593}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1URR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1URR OCA].
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==Reference==
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<ref group="xtra">PMID:15159593</ref><references group="xtra"/>
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[[Category: Acylphosphatase]]
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Bolognesi, M.]]
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[[Category: Large Structures]]
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[[Category: Rosano, C.]]
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[[Category: Bolognesi M]]
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[[Category: Zuccotti, S.]]
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[[Category: Rosano C]]
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[[Category: Acylphosphatase]]
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[[Category: Zuccotti S]]
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[[Category: Enzyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:52:59 2009''
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Current revision

A novel Drosophila Melanogaster Acylphosphatase (AcPDro2)

PDB ID 1urr

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OCA

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