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1drs

From Proteopedia

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{{Seed}}
 
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[[Image:1drs.png|left|200px]]
 
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==THREE-DIMENSIONAL STRUCTURE OF THE RGD-CONTAINING NEUROTOXIN HOMOLOGUE, DENDROASPIN==
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The line below this paragraph, containing "STRUCTURE_1drs", creates the "Structure Box" on the page.
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<StructureSection load='1drs' size='340' side='right'caption='[[1drs]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1drs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_jamesoni_kaimosae Dendroaspis jamesoni kaimosae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DRS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1drs OCA], [https://pdbe.org/1drs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1drs RCSB], [https://www.ebi.ac.uk/pdbsum/1drs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1drs ProSAT]</span></td></tr>
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{{STRUCTURE_1drs| PDB=1drs | SCENE= }}
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</table>
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== Function ==
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===THREE-DIMENSIONAL STRUCTURE OF THE RGD-CONTAINING NEUROTOXIN HOMOLOGUE, DENDROASPIN===
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[https://www.uniprot.org/uniprot/3SPM_DENJA 3SPM_DENJA] Inhibits ADP-induced platelet aggregation and inhibits the binding of purified platelet fibrinogen receptor alpha-IIb/beta-3 (ITGA2B/ITGB3) to immobilized fibrinogen (PubMed:1591238). Has also been described to inhibit cell adhesion to fibrinogen, fibronectin, laminin and collagen (PubMed:16798616, PubMed:11336631).<ref>PMID:11336631</ref> <ref>PMID:1591238</ref> <ref>PMID:16798616</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_7634091}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 7634091 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/1drs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_7634091}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1drs ConSurf].
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1DRS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Dendroaspis_jamesoni_kaimosae Dendroaspis jamesoni kaimosae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DRS OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:7634091</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Dendroaspis jamesoni kaimosae]]
[[Category: Dendroaspis jamesoni kaimosae]]
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[[Category: Hyde, E I.]]
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[[Category: Large Structures]]
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[[Category: Jaseja, M.]]
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[[Category: Hyde EI]]
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[[Category: Lu, X.]]
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[[Category: Jaseja M]]
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[[Category: Sutcliffe, M J.]]
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[[Category: Lu X]]
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[[Category: Williams, J A.]]
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[[Category: Sutcliffe MJ]]
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[[Category: Cell adhesion protein]]
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[[Category: Williams JA]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:15:34 2009''
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Current revision

THREE-DIMENSIONAL STRUCTURE OF THE RGD-CONTAINING NEUROTOXIN HOMOLOGUE, DENDROASPIN

PDB ID 1drs

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