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1t4a

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{{Seed}}
 
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[[Image:1t4a.png|left|200px]]
 
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==Structure of B. Subtilis PurS C2 Crystal Form==
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The line below this paragraph, containing "STRUCTURE_1t4a", creates the "Structure Box" on the page.
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<StructureSection load='1t4a' size='340' side='right'caption='[[1t4a]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1t4a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T4A FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1t4a| PDB=1t4a | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t4a OCA], [https://pdbe.org/1t4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t4a RCSB], [https://www.ebi.ac.uk/pdbsum/1t4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t4a ProSAT]</span></td></tr>
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</table>
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===Structure of B. Subtilis PurS C2 Crystal Form===
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== Function ==
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[https://www.uniprot.org/uniprot/PURS_BACSU PURS_BACSU] Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.[HAMAP-Rule:MF_01926]<ref>PMID:10784038</ref> <ref>PMID:15301530</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15301532 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t4/1t4a_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15301532}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1T4A is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T4A OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t4a ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:15301532</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Anand, R.]]
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[[Category: Large Structures]]
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[[Category: Bennett, E M.]]
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[[Category: Anand R]]
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[[Category: Ealick, S E.]]
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[[Category: Bennett EM]]
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[[Category: Hoskins, A A.]]
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[[Category: Ealick SE]]
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[[Category: Sintchak, M D.]]
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[[Category: Hoskins AA]]
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[[Category: Stubbe, J.]]
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[[Category: Sintchak MD]]
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[[Category: Complex formyl glycinamide synthetase]]
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[[Category: Stubbe J]]
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[[Category: Fgam]]
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[[Category: Fgar]]
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[[Category: Pur]]
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[[Category: Tetramer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:21:27 2009''
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Current revision

Structure of B. Subtilis PurS C2 Crystal Form

PDB ID 1t4a

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