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2i6t
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2i6t.png|left|200px]] | ||
| - | + | ==Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A== | |
| - | + | <StructureSection load='2i6t' size='340' side='right'caption='[[2i6t]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2i6t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I6T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i6t OCA], [https://pdbe.org/2i6t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i6t RCSB], [https://www.ebi.ac.uk/pdbsum/2i6t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i6t ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/UEVLD_HUMAN UEVLD_HUMAN] Possible negative regulator of polyubiquitination.<ref>PMID:12427560</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | == | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/2i6t_consurf.spt"</scriptWhenChecked> |
| - | < | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i6t ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Avvakumov | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Avvakumov GV]] |
| - | [[Category: Butler-Cole | + | [[Category: Bochkarev A]] |
| - | [[Category: Dhe-Paganon | + | [[Category: Butler-Cole C]] |
| - | [[Category: Edwards | + | [[Category: Dhe-Paganon S]] |
| - | [[Category: Jr | + | [[Category: Edwards AM]] |
| - | [[Category: Newman | + | [[Category: Finerty Jr PJ]] |
| - | [[Category: Sundstrom | + | [[Category: Newman EM]] |
| - | [[Category: Tempel | + | [[Category: Sundstrom M]] |
| - | [[Category: Walker | + | [[Category: Tempel W]] |
| - | [[Category: Weigelt | + | [[Category: Walker JR]] |
| - | [[Category: Xue | + | [[Category: Weigelt J]] |
| - | + | [[Category: Xue S]] | |
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Current revision
Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Avvakumov GV | Bochkarev A | Butler-Cole C | Dhe-Paganon S | Edwards AM | Finerty Jr PJ | Newman EM | Sundstrom M | Tempel W | Walker JR | Weigelt J | Xue S

