1dq5

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{{Seed}}
 
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[[Image:1dq5.png|left|200px]]
 
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==Manganese;Manganese concanavalin A at pH 5.0==
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The line below this paragraph, containing "STRUCTURE_1dq5", creates the "Structure Box" on the page.
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<StructureSection load='1dq5' size='340' side='right'caption='[[1dq5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1dq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DQ5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_1dq5| PDB=1dq5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq5 OCA], [https://pdbe.org/1dq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dq5 RCSB], [https://www.ebi.ac.uk/pdbsum/1dq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dq5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dq/1dq5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dq5 ConSurf].
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<div style="clear:both"></div>
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===Manganese;Manganese concanavalin A at pH 5.0===
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==See Also==
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*[[Concanavalin 3D structures|Concanavalin 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10748006 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_10748006}}
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==About this Structure==
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1DQ5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQ5 OCA].
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==Reference==
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<ref group="xtra">PMID:10748006</ref><references group="xtra"/>
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[[Category: Canavalia ensiformis]]
[[Category: Canavalia ensiformis]]
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[[Category: Bouckaert, J.]]
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[[Category: Large Structures]]
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[[Category: Dewallef, Y.]]
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[[Category: Bouckaert J]]
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[[Category: Loris, R.]]
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[[Category: Dewallef Y]]
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[[Category: Poortmans, F.]]
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[[Category: Loris R]]
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[[Category: Wyns, L.]]
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[[Category: Poortmans F]]
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[[Category: Binuclear]]
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[[Category: Wyns L]]
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[[Category: Concanavalin some]]
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[[Category: Lecin]]
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[[Category: Manganese]]
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[[Category: Metal binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:12:59 2009''
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Current revision

Manganese;Manganese concanavalin A at pH 5.0

PDB ID 1dq5

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