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1kkh

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{{Seed}}
 
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[[Image:1kkh.png|left|200px]]
 
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<!--
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==Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase==
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The line below this paragraph, containing "STRUCTURE_1kkh", creates the "Structure Box" on the page.
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<StructureSection load='1kkh' size='340' side='right'caption='[[1kkh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KKH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene></td></tr>
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{{STRUCTURE_1kkh| PDB=1kkh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kkh OCA], [https://pdbe.org/1kkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kkh RCSB], [https://www.ebi.ac.uk/pdbsum/1kkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kkh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MVK_METJA MVK_METJA] Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.[HAMAP-Rule:MF_00217]<ref>PMID:10497066</ref> <ref>PMID:12880770</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/1kkh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kkh ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase===
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==See Also==
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*[[Mevalonate kinase|Mevalonate kinase]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_11751891}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 11751891 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_11751891}}
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==About this Structure==
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1KKH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KKH OCA].
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==Reference==
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<ref group="xtra">PMID:11751891</ref><references group="xtra"/>
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[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Mevalonate kinase]]
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[[Category: Roessner CA]]
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[[Category: Roessner, C A.]]
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[[Category: Sacchettini JC]]
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[[Category: Sacchettini, J C.]]
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[[Category: Scott AI]]
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[[Category: Scott, A I.]]
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[[Category: Shipman LW]]
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[[Category: Shipman, L W.]]
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[[Category: Yang D]]
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[[Category: Yang, D.]]
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[[Category: Beta-alpha-beta]]
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[[Category: Mixed beta sheet]]
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[[Category: Phosphate-binding loop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:37:30 2009''
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Current revision

Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase

PDB ID 1kkh

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