1h8g
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1h8g.png|left|200px]] | ||
- | + | ==C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae== | |
- | + | <StructureSection load='1h8g' size='340' side='right'caption='[[1h8g]], [[Resolution|resolution]] 2.40Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1h8g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H8G FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHT:CHOLINE+ION'>CHT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h8g OCA], [https://pdbe.org/1h8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h8g RCSB], [https://www.ebi.ac.uk/pdbsum/1h8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h8g ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/ALYS_STRPN ALYS_STRPN] Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing cell walls for activity. | |
- | + | == Evolutionary Conservation == | |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/1h8g_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | == | + | </jmolCheckbox> |
- | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h8g ConSurf]. | |
- | + | <div style="clear:both"></div> | |
- | == | + | __TOC__ |
- | < | + | </StructureSection> |
- | [[ | + | [[Category: Large Structures]] |
[[Category: Streptococcus pneumoniae]] | [[Category: Streptococcus pneumoniae]] | ||
- | [[Category: Fernandez-Tornero | + | [[Category: Fernandez-Tornero C]] |
- | [[Category: Garcia | + | [[Category: Garcia E]] |
- | [[Category: Gimenez-Gallego | + | [[Category: Gimenez-Gallego G]] |
- | [[Category: Lopez | + | [[Category: Lopez R]] |
- | [[Category: Romero | + | [[Category: Romero A]] |
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Current revision
C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae
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