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1r4z

From Proteopedia

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{{Seed}}
 
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[[Image:1r4z.png|left|200px]]
 
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<!--
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==Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor==
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The line below this paragraph, containing "STRUCTURE_1r4z", creates the "Structure Box" on the page.
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<StructureSection load='1r4z' size='340' side='right'caption='[[1r4z]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r4z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R4Z FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RIL:[(4R)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL]METHYL+HYDROGEN+HEX-5-ENYLPHOSPHONATE'>RIL</scene></td></tr>
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{{STRUCTURE_1r4z| PDB=1r4z | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r4z OCA], [https://pdbe.org/1r4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r4z RCSB], [https://www.ebi.ac.uk/pdbsum/1r4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r4z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ESTA_BACSU ESTA_BACSU] Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups.<ref>PMID:8396026</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r4/1r4z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r4z ConSurf].
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<div style="clear:both"></div>
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===Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor===
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==See Also==
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*[[Lipase 3D Structures|Lipase 3D Structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_16342303}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16342303 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_16342303}}
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==About this Structure==
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1R4Z is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Z OCA].
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==Reference==
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<ref group="xtra">PMID:16342303</ref><references group="xtra"/>
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Triacylglycerol lipase]]
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[[Category: Large Structures]]
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[[Category: Dijkstra, B W.]]
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[[Category: Dijkstra BW]]
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[[Category: Droege, M J.]]
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[[Category: Droege MJ]]
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[[Category: Pouderoyen, G Van.]]
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[[Category: Quax WJ]]
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[[Category: Quax, W J.]]
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[[Category: Reetz MT]]
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[[Category: Reetz, M T.]]
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[[Category: Rueggeberg CJ]]
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[[Category: Rueggeberg, C J.]]
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[[Category: Van Pouderoyen G]]
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[[Category: Vrenken, T E.]]
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[[Category: Vrenken TE]]
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[[Category: Alpha/beta hydrolase]]
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[[Category: Lipase]]
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[[Category: Phosphonate inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:27:55 2009''
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Current revision

Bacillus subtilis lipase A with covalently bound Rc-IPG-phosphonate-inhibitor

PDB ID 1r4z

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