2jzj

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{{Seed}}
 
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[[Image:2jzj.png|left|200px]]
 
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==Structure of CrCVNH (C. richardii CVNH)==
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The line below this paragraph, containing "STRUCTURE_2jzj", creates the "Structure Box" on the page.
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<StructureSection load='2jzj' size='340' side='right'caption='[[2jzj]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jzj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ceratopteris_richardii Ceratopteris richardii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JZJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 30 models</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jzj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jzj OCA], [https://pdbe.org/2jzj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jzj RCSB], [https://www.ebi.ac.uk/pdbsum/2jzj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jzj ProSAT]</span></td></tr>
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{{STRUCTURE_2jzj| PDB=2jzj | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0VWW7_CERRI D0VWW7_CERRI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jz/2jzj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jzj ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Solution structures for three members of the recently discovered cyanovirin-N (CV-N) homolog family of lectins have been determined. Cyanovirin-N homologs (CVNHs) from Tuber borchii, Ceratopteris richardii, and Neurospora crassa, representing each of the three phylogenetic groups, were selected. All proteins exhibit the same fold, and the overall structures resemble that of the founding member of the family, CV-N, albeit with noteworthy differences in loop conformation and detailed local structure. Since no data are available regarding the proteins' function or their natural ligands, extensive carbohydrate-binding studies were conducted. We delineated ligand-binding sites on all three proteins by nuclear magnetic resonance and identified which sugars interact by array screening. The number and location of binding sites vary for the three proteins, and different ligand specificities exist. Potential physiological roles for two family members, TbCVNH and NcCVNH, were probed in nutrition deprivation experiments that suggest a possible involvement of these proteins in lifestyle-related responses.
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===Structure of CrCVNH (C. richardii CVNH)===
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The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity.,Koharudin LM, Viscomi AR, Jee JG, Ottonello S, Gronenborn AM Structure. 2008 Apr;16(4):570-84. PMID:18400178<ref>PMID:18400178</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_18400178}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2jzj" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 18400178 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_18400178}}
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__TOC__
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</StructureSection>
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==About this Structure==
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2JZJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Ceratopteris_richardii Ceratopteris richardii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JZJ OCA].
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==Reference==
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<ref group="xtra">PMID:18400178</ref><references group="xtra"/>
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[[Category: Ceratopteris richardii]]
[[Category: Ceratopteris richardii]]
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[[Category: Gronenborn, A M.]]
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[[Category: Large Structures]]
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[[Category: Jee, J.]]
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[[Category: Gronenborn AM]]
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[[Category: Koharudin, L M.I.]]
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[[Category: Jee J]]
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[[Category: Ottonello, S.]]
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[[Category: Koharudin LMI]]
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[[Category: Viscomi, A R.]]
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[[Category: Ottonello S]]
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[[Category: Antiviral protein]]
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[[Category: Viscomi AR]]
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[[Category: Carbohydrate binding protein]]
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[[Category: Cvnh]]
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[[Category: Nmr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:00:48 2009''
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Current revision

Structure of CrCVNH (C. richardii CVNH)

PDB ID 2jzj

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