1gd6

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{{Seed}}
 
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[[Image:1gd6.png|left|200px]]
 
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==STRUCTURE OF THE BOMBYX MORI LYSOZYME==
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The line below this paragraph, containing "STRUCTURE_1gd6", creates the "Structure Box" on the page.
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<StructureSection load='1gd6' size='340' side='right'caption='[[1gd6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1gd6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GD6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gd6 OCA], [https://pdbe.org/1gd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gd6 RCSB], [https://www.ebi.ac.uk/pdbsum/1gd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gd6 ProSAT]</span></td></tr>
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{{STRUCTURE_1gd6| PDB=1gd6 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYS_BOMMO LYS_BOMMO] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Active against E.coli and M.luteus.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/1gd6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gd6 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme. BmLZ has considerable activity at low temperatures and low activation energies compared with those of hen egg white lysozyme (HEWLZ), according to measurements of the temperature dependencies of relative activity (lytic and glycol chitin) and the estimation of activation energies using the Arrhenius equation. Being so active at low temperatures and low activation energies is characteristic of psychrophilic (cold-adapted) enzymes. The three-dimensional structure of BmLZ has been determined by X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is similar to that of c-type lysozymes. However, BmLZ shows some distinct differences in the two exposed loops and the C-terminal region. A detailed comparison of BmLZ and HEWLZ suggests structural rationalizations for the differences in the catalytic efficiency, stability, and mode of activity between these two lysozymes.
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===STRUCTURE OF THE BOMBYX MORI LYSOZYME===
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Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures.,Matsuura A, Yao M, Aizawa T, Koganesawa N, Masaki K, Miyazawa M, Demura M, Tanaka I, Kawano K, Nitta K Biochemistry. 2002 Oct 8;41(40):12086-92. PMID:12356308<ref>PMID:12356308</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1gd6" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_12356308}}, adds the Publication Abstract to the page
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12356308 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_12356308}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1GD6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GD6 OCA].
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==Reference==
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<ref group="xtra">PMID:12356308</ref><references group="xtra"/>
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[[Category: Bombyx mori]]
[[Category: Bombyx mori]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Aizawa, T.]]
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[[Category: Aizawa T]]
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[[Category: Kawano, K.]]
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[[Category: Kawano K]]
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[[Category: Matsuura, A.]]
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[[Category: Matsuura A]]
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[[Category: Nitta, K.]]
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[[Category: Nitta K]]
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[[Category: Tanaka, I.]]
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[[Category: Tanaka I]]
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[[Category: Yao, M.]]
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[[Category: Yao M]]
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[[Category: 4-beta-n-acetylmuramidase]]
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[[Category: Bmlz]]
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[[Category: Lysozyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:21:05 2009''
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Current revision

STRUCTURE OF THE BOMBYX MORI LYSOZYME

PDB ID 1gd6

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