This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1cwf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:44, 13 March 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1cwf.png|left|200px]]
 
-
<!--
+
==HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN==
-
The line below this paragraph, containing "STRUCTURE_1cwf", creates the "Structure Box" on the page.
+
<StructureSection load='1cwf' size='340' side='right'caption='[[1cwf]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1cwf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CWF FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
-
{{STRUCTURE_1cwf| PDB=1cwf | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwf OCA], [https://pdbe.org/1cwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cwf RCSB], [https://www.ebi.ac.uk/pdbsum/1cwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cwf ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/1cwf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cwf ConSurf].
 +
<div style="clear:both"></div>
-
===HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN===
+
==See Also==
-
 
+
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_9769216}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 9769216 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_9769216}}
+
-
 
+
-
==About this Structure==
+
-
1CWF is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CWF OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:9769216</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Peptidylprolyl isomerase]]
+
[[Category: Large Structures]]
-
[[Category: Kallen, J.]]
+
[[Category: Tolypocladium inflatum]]
-
[[Category: Mikol, V.]]
+
[[Category: Kallen J]]
-
[[Category: Taylor, P.]]
+
[[Category: Mikol V]]
-
[[Category: Walkinshaw, M D.]]
+
[[Category: Taylor P]]
-
 
+
[[Category: Walkinshaw MD]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:22:12 2009''
+

Current revision

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN

PDB ID 1cwf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cwf"
Personal tools