3csq

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{{Seed}}
 
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[[Image:3csq.png|left|200px]]
 
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==Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail==
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The line below this paragraph, containing "STRUCTURE_3csq", creates the "Structure Box" on the page.
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<StructureSection load='3csq' size='340' side='right'caption='[[3csq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3csq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_phi29 Bacillus phage phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CSQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3csq| PDB=3csq | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3csq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3csq OCA], [https://pdbe.org/3csq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3csq RCSB], [https://www.ebi.ac.uk/pdbsum/3csq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3csq ProSAT]</span></td></tr>
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</table>
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===Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail===
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== Function ==
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[https://www.uniprot.org/uniprot/GP13_BPPH2 GP13_BPPH2] May serve as a plug to restrain the highly pressurized packaged genome and thus would be the first virion protein to contact the host cell wall, degrading the peptidoglycan layer and thereby facilitating viral genome entry into the host bacteria. Acts probably as a multifunctional enzyme that degrades N-acetylglucosamine polymers (in vitro) and cleaves the peptide cross-links of the host cell wall. Essential for the tail assembly.<ref>PMID:18394643</ref> <ref>PMID:18606992</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18606992}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18606992 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/3csq_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18606992}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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3CSQ is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_phage_phi29 Bacillus phage phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CSQ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3csq ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:18606992</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus phage phi29]]
[[Category: Bacillus phage phi29]]
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[[Category: Rossmann, M G.]]
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[[Category: Large Structures]]
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[[Category: Xiang, Y.]]
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[[Category: Rossmann MG]]
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[[Category: Hydrolase]]
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[[Category: Xiang Y]]
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[[Category: Infection]]
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[[Category: Late protein]]
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[[Category: Phi29]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:24:32 2009''
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Current revision

Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail

PDB ID 3csq

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