1k0o

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:43, 7 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1k0o.png|left|200px]]
 
-
<!--
+
==Crystal structure of a soluble form of CLIC1. An intracellular chloride ion channel==
-
The line below this paragraph, containing "STRUCTURE_1k0o", creates the "Structure Box" on the page.
+
<StructureSection load='1k0o' size='340' side='right'caption='[[1k0o]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1k0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K0O FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0o OCA], [https://pdbe.org/1k0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k0o RCSB], [https://www.ebi.ac.uk/pdbsum/1k0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k0o ProSAT]</span></td></tr>
-
{{STRUCTURE_1k0o| PDB=1k0o | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/1k0o_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k0o ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of a soluble form of CLIC1. An intracellular chloride ion channel===
+
==See Also==
-
 
+
*[[Ion channels 3D structures|Ion channels 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11551966}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 11551966 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_11551966}}
+
-
 
+
-
==About this Structure==
+
-
1K0O is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0O OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:11551966</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Bauskin, A R.]]
+
[[Category: Large Structures]]
-
[[Category: Breit, S N.]]
+
[[Category: Bauskin AR]]
-
[[Category: Campbell, T J.]]
+
[[Category: Breit SN]]
-
[[Category: Curmi, P M.G.]]
+
[[Category: Campbell TJ]]
-
[[Category: DeMaere, M Z.]]
+
[[Category: Curmi PMG]]
-
[[Category: Fairlie, W D.]]
+
[[Category: DeMaere MZ]]
-
[[Category: Harrop, S J.]]
+
[[Category: Fairlie WD]]
-
[[Category: Jankova, L.]]
+
[[Category: Harrop SJ]]
-
[[Category: Mazzanti, M.]]
+
[[Category: Jankova L]]
-
[[Category: Pankhurst, S.]]
+
[[Category: Mazzanti M]]
-
[[Category: Qiu, M R.]]
+
[[Category: Pankhurst S]]
-
[[Category: Reztsova, T.]]
+
[[Category: Qiu MR]]
-
[[Category: Tonini, R.]]
+
[[Category: Reztsova T]]
-
[[Category: Valenzuela, S M.]]
+
[[Category: Tonini R]]
-
[[Category: Warton, K.]]
+
[[Category: Valenzuela SM]]
-
[[Category: Wu, W M.]]
+
[[Category: Warton K]]
-
[[Category: Chloride ion channel]]
+
[[Category: Wu WM]]
-
[[Category: Clic1]]
+
-
[[Category: Glutathione-s-transferase superfamily]]
+
-
[[Category: Ncc27]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:30:00 2009''
+

Current revision

Crystal structure of a soluble form of CLIC1. An intracellular chloride ion channel

PDB ID 1k0o

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1k0o"
Personal tools