1jot
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1jot.png|left|200px]] | ||
- | < | + | ==STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE== |
- | + | <StructureSection load='1jot' size='340' side='right'caption='[[1jot]], [[Resolution|resolution]] 2.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1jot]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Maclura_pomifera Maclura pomifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JOT FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jot OCA], [https://pdbe.org/1jot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jot RCSB], [https://www.ebi.ac.uk/pdbsum/1jot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jot ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/LECA_MACPO LECA_MACPO] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jo/1jot_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jot ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Agglutinin 3D structures|Agglutinin 3D structures]] | |
- | + | __TOC__ | |
- | < | + | </StructureSection> |
- | + | [[Category: Large Structures]] | |
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[[Category: Maclura pomifera]] | [[Category: Maclura pomifera]] | ||
- | [[Category: Biesterfeldt | + | [[Category: Biesterfeldt J]] |
- | [[Category: Hoa | + | [[Category: Hoa T-T]] |
- | [[Category: Johnston | + | [[Category: Johnston RAZ]] |
- | [[Category: Lee | + | [[Category: Lee X]] |
- | [[Category: Ogata | + | [[Category: Ogata C]] |
- | [[Category: Thompson | + | [[Category: Thompson A]] |
- | [[Category: Xu | + | [[Category: Xu L]] |
- | [[Category: Young | + | [[Category: Young NM]] |
- | [[Category: Zhang | + | [[Category: Zhang Z]] |
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Current revision
STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE
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Categories: Large Structures | Maclura pomifera | Biesterfeldt J | Hoa T-T | Johnston RAZ | Lee X | Ogata C | Thompson A | Xu L | Young NM | Zhang Z