1bar
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1bar.png|left|200px]] | ||
- | + | ==THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS== | |
- | + | <StructureSection load='1bar' size='340' side='right'caption='[[1bar]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1bar]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BAR FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bar OCA], [https://pdbe.org/1bar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bar RCSB], [https://www.ebi.ac.uk/pdbsum/1bar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bar ProSAT]</span></td></tr> | |
- | + | </table> | |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/FGF1_BOVIN FGF1_BOVIN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:9712834</ref> <ref>PMID:11039909</ref> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/1bar_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bar ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]] | |
- | + | == References == | |
- | + | <references/> | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
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- | == | + | |
- | < | + | |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
- | [[Category: Arakawa | + | [[Category: Large Structures]] |
- | [[Category: Chirino | + | [[Category: Arakawa T]] |
- | [[Category: Faham | + | [[Category: Chirino A]] |
- | [[Category: Fox | + | [[Category: Faham S]] |
- | [[Category: Hsu | + | [[Category: Fox GM]] |
- | [[Category: Komiya | + | [[Category: Hsu BT]] |
- | [[Category: Rees | + | [[Category: Komiya H]] |
- | [[Category: Zhu | + | [[Category: Rees DC]] |
- | + | [[Category: Zhu X]] | |
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Current revision
THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS
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Categories: Bos taurus | Large Structures | Arakawa T | Chirino A | Faham S | Fox GM | Hsu BT | Komiya H | Rees DC | Zhu X