1yhd

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{{Seed}}
 
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[[Image:1yhd.png|left|200px]]
 
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==The solution structure of YGGX from Escherichia Coli==
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The line below this paragraph, containing "STRUCTURE_1yhd", creates the "Structure Box" on the page.
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<StructureSection load='1yhd' size='340' side='right'caption='[[1yhd]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yhd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YHD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yhd OCA], [https://pdbe.org/1yhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yhd RCSB], [https://www.ebi.ac.uk/pdbsum/1yhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yhd ProSAT]</span></td></tr>
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{{STRUCTURE_1yhd| PDB=1yhd | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FETP_ECOLI FETP_ECOLI] Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. Necessary to maintain high levels of aconitase under oxidative stress.<ref>PMID:14594836</ref> <ref>PMID:15883188</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yh/1yhd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yhd ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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YggX is a highly conserved protein found only in eubacteria and is proposed to be involved in the bacterial response to oxidative stress. Here we report the solution structure of YggX from Escherichia coli determined by nuclear magnetic resonance spectroscopy. The structure of YggX displays a fold consisting of two N-terminal antiparallel beta-sheets and three alpha-helices, which shares significant structural similarity to the crystal structure of a hypothetical protein PA5148 from Pseudomonas aeruginosa. Previous studies propose YggX as an iron binding protein that is involved in cellular iron trafficking. Our data indicate that the protein alone does not bind iron in vitro, suggesting other cofactors or different conditions may be necessary for metal binding.
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===The solution structure of YGGX from Escherichia Coli===
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The solution structure of the oxidative stress-related protein YggX from Escherichia coli.,Osborne MJ, Siddiqui N, Landgraf D, Pomposiello PJ, Gehring K Protein Sci. 2005 Jun;14(6):1673-8. Epub 2005 May 9. PMID:15883188<ref>PMID:15883188</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_15883188}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1yhd" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 15883188 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_15883188}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1YHD is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YHD OCA].
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==Reference==
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<ref group="xtra">PMID:15883188</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Gehring, K.]]
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[[Category: Large Structures]]
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[[Category: Landgraf, D.]]
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[[Category: Gehring K]]
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[[Category: Osborne, M J.]]
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[[Category: Landgraf D]]
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[[Category: Pomposiello, P J.]]
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[[Category: Osborne MJ]]
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[[Category: Siddiqui, N.]]
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[[Category: Pomposiello PJ]]
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[[Category: Helix bundle]]
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[[Category: Siddiqui N]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:48:54 2009''
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Current revision

The solution structure of YGGX from Escherichia Coli

PDB ID 1yhd

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