1t56

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{{Seed}}
 
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[[Image:1t56.png|left|200px]]
 
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==Crystal structure of TetR family repressor M. tuberculosis EthR==
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The line below this paragraph, containing "STRUCTURE_1t56", creates the "Structure Box" on the page.
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<StructureSection load='1t56' size='340' side='right'caption='[[1t56]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1t56]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T56 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T56 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_1t56| PDB=1t56 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t56 OCA], [https://pdbe.org/1t56 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t56 RCSB], [https://www.ebi.ac.uk/pdbsum/1t56 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t56 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t5/1t56_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t56 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of TetR family repressor M. tuberculosis EthR===
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==See Also==
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 15236969 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_15236969}}
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Besra GS]]
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==About this Structure==
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[[Category: Cocklin SL]]
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1T56 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T56 OCA].
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[[Category: Corsino PE]]
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[[Category: Daniels IR]]
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==Reference==
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[[Category: Dover LG]]
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<ref group="xtra">PMID:15236969</ref><references group="xtra"/>
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[[Category: Futterer K]]
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[[Category: Mycobacterium tuberculosis h37rv]]
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[[Category: Tatituri V]]
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[[Category: Besra, G S.]]
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[[Category: Cocklin, S L.]]
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[[Category: Corsino, P E.]]
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[[Category: Daniels, I R.]]
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[[Category: Dover, L G.]]
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[[Category: Futterer, K.]]
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[[Category: Tatituri, V.]]
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[[Category: Dimer]]
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[[Category: Helix-turn-helix]]
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[[Category: Tetr family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:41:29 2009''
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Current revision

Crystal structure of TetR family repressor M. tuberculosis EthR

PDB ID 1t56

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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