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1jac

From Proteopedia

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{{Seed}}
 
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[[Image:1jac.png|left|200px]]
 
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==A NOVEL MODE OF CARBOHYDRATE RECOGNITION IN JACALIN, A MORACEAE PLANT LECTIN WITH A BETA-PRISM==
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The line below this paragraph, containing "STRUCTURE_1jac", creates the "Structure Box" on the page.
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<StructureSection load='1jac' size='340' side='right'caption='[[1jac]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jac]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_heterophyllus Artocarpus heterophyllus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JAC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMG:ALPHA-METHYL-D-GALACTOSIDE'>AMG</scene></td></tr>
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{{STRUCTURE_1jac| PDB=1jac | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jac OCA], [https://pdbe.org/1jac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jac RCSB], [https://www.ebi.ac.uk/pdbsum/1jac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jac ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/1jac_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jac ConSurf].
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<div style="clear:both"></div>
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===A NOVEL MODE OF CARBOHYDRATE RECOGNITION IN JACALIN, A MORACEAE PLANT LECTIN WITH A BETA-PRISM===
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==See Also==
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8673603}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8673603 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8673603}}
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==About this Structure==
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1JAC is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Artocarpus_heterophyllus Artocarpus heterophyllus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAC OCA].
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==Reference==
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<ref group="xtra">PMID:8673603</ref><references group="xtra"/>
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[[Category: Artocarpus heterophyllus]]
[[Category: Artocarpus heterophyllus]]
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[[Category: Banerjee, R.]]
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[[Category: Large Structures]]
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[[Category: Sankaranarayanan, R.]]
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[[Category: Banerjee R]]
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[[Category: Sekar, K.]]
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[[Category: Sankaranarayanan R]]
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[[Category: Sharma, V.]]
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[[Category: Sekar K]]
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[[Category: Surolia, A.]]
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[[Category: Sharma V]]
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[[Category: Vijayan, M.]]
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[[Category: Surolia A]]
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[[Category: Beta-prism fold]]
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[[Category: Vijayan M]]
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[[Category: Carbohydrate specificity]]
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[[Category: Glycoprotein]]
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[[Category: Lectin]]
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[[Category: Non-legume]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:48:30 2009''
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Current revision

A NOVEL MODE OF CARBOHYDRATE RECOGNITION IN JACALIN, A MORACEAE PLANT LECTIN WITH A BETA-PRISM

PDB ID 1jac

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