1ejb

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{{Seed}}
 
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[[Image:1ejb.png|left|200px]]
 
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==LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE==
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The line below this paragraph, containing "STRUCTURE_1ejb", creates the "Structure Box" on the page.
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<StructureSection load='1ejb' size='340' side='right'caption='[[1ejb]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ejb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=INJ:5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC+ACID'>INJ</scene></td></tr>
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{{STRUCTURE_1ejb| PDB=1ejb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ejb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ejb OCA], [https://pdbe.org/1ejb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ejb RCSB], [https://www.ebi.ac.uk/pdbsum/1ejb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ejb ProSAT]</span></td></tr>
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</table>
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===LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE===
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== Function ==
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[https://www.uniprot.org/uniprot/RIB4_YEAST RIB4_YEAST] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<ref>PMID:7559556</ref> <ref>PMID:8969176</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10860731}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10860731 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/1ejb_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10860731}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1EJB is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJB OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ejb ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:10860731</ref><references group="xtra"/>
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<references/>
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[[Category: Riboflavin synthase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Bacher, A.]]
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[[Category: Bacher A]]
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[[Category: Cushman, M.]]
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[[Category: Cushman M]]
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[[Category: Fischer, M.]]
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[[Category: Fischer M]]
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[[Category: Ladenstein, R.]]
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[[Category: Ladenstein R]]
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[[Category: Meining, W.]]
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[[Category: Meining W]]
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[[Category: Mortl, S.]]
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[[Category: Mortl S]]
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[[Category: Inhibitor complex]]
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[[Category: Lumazine synthase]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Vitamin biosynthesis]]
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[[Category: X-ray structure analysis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:10:27 2009''
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Current revision

LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE

PDB ID 1ejb

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