1ejb
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1ejb.png|left|200px]] | ||
- | + | ==LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE== | |
- | + | <StructureSection load='1ejb' size='340' side='right'caption='[[1ejb]], [[Resolution|resolution]] 1.85Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1ejb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJB FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=INJ:5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC+ACID'>INJ</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ejb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ejb OCA], [https://pdbe.org/1ejb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ejb RCSB], [https://www.ebi.ac.uk/pdbsum/1ejb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ejb ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/RIB4_YEAST RIB4_YEAST] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<ref>PMID:7559556</ref> <ref>PMID:8969176</ref> | |
- | + | == Evolutionary Conservation == | |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/1ejb_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | == | + | </jmolCheckbox> |
- | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ejb ConSurf]. | |
- | + | <div style="clear:both"></div> | |
- | == | + | == References == |
- | < | + | <references/> |
- | [[Category: | + | __TOC__ |
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
- | [[Category: Bacher | + | [[Category: Bacher A]] |
- | [[Category: Cushman | + | [[Category: Cushman M]] |
- | [[Category: Fischer | + | [[Category: Fischer M]] |
- | [[Category: Ladenstein | + | [[Category: Ladenstein R]] |
- | [[Category: Meining | + | [[Category: Meining W]] |
- | [[Category: Mortl | + | [[Category: Mortl S]] |
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Current revision
LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE
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