2fdq

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{{Seed}}
 
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[[Image:2fdq.png|left|200px]]
 
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==crystal structure of ACBP from Armadillo Harderian Gland==
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The line below this paragraph, containing "STRUCTURE_2fdq", creates the "Structure Box" on the page.
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<StructureSection load='2fdq' size='340' side='right'caption='[[2fdq]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fdq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetophractus_villosus Chaetophractus villosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FDQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fdq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fdq OCA], [https://pdbe.org/2fdq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fdq RCSB], [https://www.ebi.ac.uk/pdbsum/2fdq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fdq ProSAT]</span></td></tr>
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{{STRUCTURE_2fdq| PDB=2fdq | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACBP_CHAVI ACBP_CHAVI] Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/2fdq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fdq ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein (ACBP) from the Harderian gland of the South American armadillo Chaetophractus villosus has been solved. ACBP is a carrier for activated long-chain fatty acids and has been associated with many aspects of lipid metabolism. Its secondary structure is highly similar to that of the corresponding form of bovine ACBP and exhibits the unique flattened alpha-helical bundle (up-down-down-up) motif reported for animal, yeast and insect ACBPs. Conformational differences are located in loops and turns, although these structural differences do not suffice to account for features that could be related to the unusual biochemistry and lipid metabolism of the Harderian gland.
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===crystal structure of ACBP from Armadillo Harderian Gland===
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Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family.,Costabel MD, Ermacora MR, Santome JA, Alzari PM, Guerin DM Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt, 10):958-61. Epub 2006 Sep 30. PMID:17012783<ref>PMID:17012783</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_17012783}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2fdq" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 17012783 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_17012783}}
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__TOC__
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</StructureSection>
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==About this Structure==
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2FDQ is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Chaetophractus_villosus Chaetophractus villosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDQ OCA].
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==Reference==
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<ref group="xtra">PMID:17012783</ref><references group="xtra"/>
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[[Category: Chaetophractus villosus]]
[[Category: Chaetophractus villosus]]
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[[Category: Costabel, M D.]]
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[[Category: Large Structures]]
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[[Category: Guerin, D M.A.]]
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[[Category: Costabel MD]]
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[[Category: Acbp]]
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[[Category: Guerin DMA]]
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[[Category: Diazepam binding inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:22:34 2009''
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Current revision

crystal structure of ACBP from Armadillo Harderian Gland

PDB ID 2fdq

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